Posted in Library of Congress, Undogegorized by chamblee54 on August 27, 2021

I had never heard of Ivermectin (IVM) before June 22, 2021. That was the day of the “emergency episode” of the Joe Rogan Experience, featuring Bret Weinstein & Dr. Pierre Kory. The story they told was jaw dropping. An established drug, Ivermectin, was showing great promise against Covid 19. IVM worked both as a treatment, and as a prophylactic against infection. There were stories about use in Mexico and India, with positive results. Unfortunately, the patent on IVM had expired. There was no promise of windfall profits to encourage lab testing. I saw about 45 minutes of the show, and felt confused by all the conflicting information.

@BretWeinstein “YouTube just demonetized both DarkHorse channels, wiping out more than half our family income. Their message: Drop the science and stick to the narrative—or else. No, YouTube. Review *this* video. #CensorshipKills, belts tighten, incomes can be replaced.” Dr. Weinstein was promptly punished for his good deed. Apparently, someone in the government/pharmaceutical/google collaborative does not want to have a discussion of IVM.

Fifty years ago, the target of FDA ire was marijuana. Stories of potential medical uses had been circulating for years. However, there was little research. “In 1970, the federal government classified marijuana as an illegal, highly addictive drug with no medical value, making research harder to do.” Any medical benefits could be obtained through the use of synthetic, industrial chemical medicine.

In the eight weeks after the Rogan emergency, Covid has gotten worse. The vaccine euphoria has been replaced by a delta depression. People are looking for solutions, and not believing what big brother says. They heard about IVM, and are not accepting the official story. Unfortunately, many people are taking matters into their own hands, and buying IVM from livestock suppliers. A festive alert from Mississippi State Department of Health notes “Animal drugs are highly concentrated for large animals and can be highly toxic in humans.”

I began to ask questions after the memes started popping up. I went to google, with the question is ivermectin approved for humans? With one exception, the first page of google was devoted to tabloid nonsense. While there are scientific documents the message can be reduced to this tweet: @US_FDA “You are not a horse. You are not a cow. Seriously, y’all. Stop it.”

Google is not the only search engine, so far. When you go elsewhere, or ask different questions, a different story emerges. “Hailed as a wonder drug for tropical diseases, ivermectin is used to treat parasitic infections in humans, pets, and livestock. This drug has alleviated the burden of river blindness and strongyloidiasis for millions of people.” Yes, IVM “has been established as safe for human use.” Humans require a different dosage than livestock.

The FDA-approved drug ivermectin inhibits the replication of SARS-CoV-2 in vitro is the one pro-IVM result on the google first page. As the title indicates, this is a scientific paper. The bullet points are enlightening: “Ivermectin is an inhibitor of the COVID-19 causative virus (SARS-CoV-2) in vitro. ~ A single treatment able to effect ~5000-fold reduction in virus at 48 h in cell culture. ~ Ivermectin is FDA-approved for parasitic infections, and therefore has a potential for repurposing. ~ Ivermectin is widely available, due to its inclusion on the WHO model list of essential medicines.”

“Ivermectin is an FDA-approved broad-spectrum antiparasitic agent with demonstrated antiviral activity against a number of DNA and RNA viruses, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Despite this promise, the antiviral activity of ivermectin has not been consistently proven in vivo. While ivermectin’s activity against SARS-CoV-2 is currently under investigation in patients, insufficient emphasis has been placed on formulation challenges. Here, we discuss challenges surrounding the use of ivermectin in the context of COVID-19. and how novel formulations employing micro- and nanotechnologies may address these concerns.”

River blindness is an IVM success story mentioned on the Rogan emergency. “River blindness (onchocerciasis) is caused by the parasitic worm Onchocerca volvulus …causes severe itching, disfiguring skin conditions and visual impairment, including blindness. More than 99% of infected people live in 31 African countries. Ivermectin, the only drug currently in use, distributed annually to entire communities living in endemic areas, has significantly reduced river blindness … ”

Weinstein & Kory discussed using IVM as a Covid treatment in several foreign countries. Since this post is getting TL/DR, there will be no quotes from these stories. (one two three four five) Online Prescription Ivermectin is available. Pictures today are from The Library of Congress. The spell check suggestions for Ivermectin: Invective, Interactive.

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